在鸡的系统中，一种依赖RNA的DNA聚合酶，与已知的病毒逆转录酶不同。
An RNA-dependent DNA polymerase, different from the known viral reverse transcriptases, in the chicken system.
作者信息
Bauer G, Hofschneider P H
出版信息
Proc Natl Acad Sci U S A. 1976 Sep;73(9):3025-9. doi: 10.1073/pnas.73.9.3025.
Abstract
The properties of an RNA-dependent DNA polymerase (an RNA-dependent DNA nucleotidyltransferase), which occurs ubiquitously in the allantoic fluid of uninfected, leukosis-virus-free eggs, are described. It is shown that the enzyme can synthesize faithful transcripts from natural RNA (globin mRNA). By biochemical and immunological methods, the enzyme can be clearly distinguished from the reverse transcriptases of the known chicken RNA tumor viruses and therefore seems to be a member of a so far unknown class of chicken polymerases.
摘要
本文描述了一种依赖RNA的DNA聚合酶（一种依赖RNA的DNA核苷酸转移酶）的特性，该酶普遍存在于未感染、无白血病病毒的鸡蛋尿囊液中。研究表明，这种酶能够从天然RNA（珠蛋白mRNA）合成忠实的转录本。通过生化和免疫学方法，该酶能够与已知鸡RNA肿瘤病毒的逆转录酶明显区分开来，因此似乎属于一类迄今未知的鸡聚合酶。
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本文引用的文献
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Purification and properties of DNA polymerases from chick embryo.鸡胚DNA聚合酶的纯化及性质
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Endogenous RNA-directed DNA polymerase activity in uninfected chicken embryos.未感染鸡胚中的内源性RNA指导的DNA聚合酶活性
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In vitro synthesis of DNA complementary to purified rabbit globin mRNA (RNA-dependent DNA polymerase-reticulocyte-hemoglobin-density gradient centrifugation-oligo(dT) primer).与纯化的兔珠蛋白信使核糖核酸互补的DNA的体外合成（RNA依赖性DNA聚合酶-网织红细胞-血红蛋白密度梯度离心-寡聚（dT）引物）
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RNA-dependent DNA polymerase in virions of Rous sarcoma virus.劳氏肉瘤病毒病毒粒子中的RNA依赖性DNA聚合酶。
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RNA-dependent DNA polymerase in virions of RNA tumour viruses.RNA肿瘤病毒病毒粒子中的RNA依赖性DNA聚合酶。
Nature. 1970 Jun 27;226(5252):1209-11. doi: 10.1038/2261209a0.
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