Plowman P N, Flemans R J
J Clin Pathol. 1980 Aug;33(8):738-43. doi: 10.1136/jcp.33.8.738.
Human pulmonary macrophages from heavy smokers usually (17/21 cases) contain sea blue inclusion material in the cytoplasm. In non-smokers, sea blue material is rarely evident (1/21 cases). The sea blue material observed has the same properties as sea blue material identified in other conditions (viz, Sudan black and PAS positivity and autofluorescence). Evidence is presented which suggests that pulmonary macrophages from smokers contain extra surfactant and that it is this phospholipid complex that accounts for the sea blue reaction observed.
重度吸烟者的人肺巨噬细胞通常（21例中有17例）在细胞质中含有海蓝色包涵体物质。在非吸烟者中，海蓝色物质很少见（21例中有1例）。观察到的海蓝色物质与在其他情况下鉴定出的海蓝色物质具有相同的特性（即，苏丹黑和过碘酸雪夫染色阳性以及自发荧光）。有证据表明，吸烟者的肺巨噬细胞含有额外的表面活性剂，正是这种磷脂复合物导致了观察到的海蓝色反应。
