Hernández-Jáuregui P, González-Vega D, Cruz-Lavín E, Hernández-Baumgarten E
Am J Vet Res. 1980 Sep;41(9):1475-8.
The in vitro effect of isoprinosine, an antiviral compound, was evaluated on ERA and VA319 rabies viral strains. Isoprinosine diminished the number of immunofluorescent cells, viral titers, and structures involved in rabies virus replication. Mechanism of antiviral action was probably mediated by modification of the polyribosome conformation and function.
对一种抗病毒化合物异丙肌苷在体外对ERA和VA319狂犬病病毒株的作用进行了评估。异丙肌苷减少了免疫荧光细胞的数量、病毒滴度以及参与狂犬病病毒复制的结构。抗病毒作用机制可能是通过多核糖体构象和功能的改变介导的。
