Nakamura W, Nagano Y, Otsuka K, Nishimoto Y
C R Seances Soc Biol Fil. 1980;174(1):104-7.
The interferon inducing effect of hyperthermia was studied in normal and tumor-bearing mice. Circulating interferon was temporarily detected one day after subcutaneous transplantation of 1.6 X 10(6) Ehrlich's ascites tumor cells. Hyperthermia of 43.5 degrees C for 5 min did not induce the interferon formation in mice with or without subcutaneous tumor of the cells. These findings showed that the induction of interferon formation was not main cause of the hyperthermia-induced tumor inhibition.
在正常小鼠和荷瘤小鼠中研究了热疗的干扰素诱导作用。在皮下接种1.6×10⁶个艾氏腹水瘤细胞一天后，可暂时检测到循环中的干扰素。43.5℃热疗5分钟，无论小鼠有无皮下肿瘤细胞，均未诱导干扰素形成。这些结果表明，干扰素形成的诱导不是热疗诱导肿瘤抑制的主要原因。
