Surface immunoglobulin-bearing rabbit lymphocytes express both VH and L chain allotypic determinants.

The cell surface distributions of a locus and b lucus rabbit immunoglobulin allotypes have been examined simultaneously, using immunoelectronmicroscopic techniques. Most rabbit lymphocytes that bear surface immunoglobulin express both a and b markers. This is true of lymphocytes from blood, spleen, and lymph node of normal and immunized rabbits. A preponderance of cells bearing VH markers (a locus) but not L chain markers (b locus) was not observed.