Imanishi J, Matsubara M, Kishida T, Ozaki Y, Kurimura T
Biken J. 1980 Sep;23(3):107-11.
The sensitivities to human leukocyte interferon of 10 strains of Herpes simplex virus (HSV) type 1 and 3 strains of type 2 were compared. All the strains were sensitive to interferon, although their sensitivities were less than that of vesicular stomatitis virus (VSV). There was no significant difference in the sensitivities to interferon of HSV type 1 and type-2 or among different strains of a given type of HSV. Nor was there any difference between the sensitivities of 5-iodo-2'-deoxyuridine (IDU)-sensitive and resistant strains isolated from the same patients. These results suggest that interferon should be useful in therapy of HSV infection.
比较了10株1型单纯疱疹病毒（HSV）和3株2型单纯疱疹病毒对人白细胞干扰素的敏感性。所有毒株对干扰素均敏感，尽管它们的敏感性低于水疱性口炎病毒（VSV）。1型和2型HSV对干扰素的敏感性之间或给定类型HSV的不同毒株之间没有显著差异。从同一患者分离出的对5-碘-2'-脱氧尿苷（IDU）敏感和耐药的毒株之间的敏感性也没有差异。这些结果表明干扰素在HSV感染的治疗中应该是有用的。
