从参与临床试验的患者中分离出的单纯疱疹病毒株的干扰素敏感性
Interferon susceptibility of herpes simplex virus strains isolated from patients enrolled in clinical trials.
作者信息
Armstrong J A, Skicki-Mullen M B, Breinig M K, Ho M
出版信息
Antimicrob Agents Chemother. 1983 Jul;24(1):137-9. doi: 10.1128/AAC.24.1.137.
Abstract
Herpes simplex virus type 1 strains isolated from patients who had received interferon in a clinical trial were not more resistant to human leukocyte interferon than strains derived from recipients of a placebo. The susceptibility of herpes simplex virus type 2 strains isolated from herpes genitalis was slightly less than that of herpes simplex virus type 1 strains causing herpes genitalis.
摘要
在一项临床试验中，从接受干扰素治疗的患者身上分离出的1型单纯疱疹病毒毒株，与从接受安慰剂治疗的患者身上分离出的毒株相比，对人白细胞干扰素的耐药性并无增强。从生殖器疱疹患者身上分离出的2型单纯疱疹病毒毒株的敏感性略低于引起生殖器疱疹的1型单纯疱疹病毒毒株。
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