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假性剥脱综合征患者眼部的虹膜新生血管形成

Iris neovascularisation in eyes with pseudoexfoliation syndrome.

作者信息

Ringvold A, Davanger M

出版信息

Br J Ophthalmol. 1981 Feb;65(2):138-41. doi: 10.1136/bjo.65.2.138.

DOI:10.1136/bjo.65.2.138
PMID:6161638
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1039443/
Abstract

The iris vascular bed of eyes with pseudoexfoliation syndrome has been studied with electron microscopy. Two of the eyes suffered from painful glaucoma, whereas the third showed normal intraocular pressure. The following changes were observed: (1) deposits of pseudoexfoliation material lying adjacent to the endothelial wall; (2) thin vessel basement membrane, sometimes even interrupted; (3) extreme reduction of vessel lumina through increased volume of the endothelial cells; (4) fenestration of the endothelial wall. It is suggested that the iris neovascularisation in eyes with pseudoexfoliation syndrome is due to an obstruction of iris vessels causing tissue hypoxia.

摘要

已采用电子显微镜对假性剥脱综合征患者眼睛的虹膜血管床进行了研究。其中两只眼睛患有疼痛性青光眼,而第三只眼睛眼压正常。观察到以下变化:(1)假性剥脱物质沉积于内皮细胞壁附近;(2)血管基底膜变薄,有时甚至中断;(3)内皮细胞体积增加导致血管腔极度狭窄;(4)内皮细胞壁出现窗孔。有人提出,假性剥脱综合征患者眼睛的虹膜新生血管形成是由于虹膜血管阻塞导致组织缺氧所致。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fccc/1039443/aa398c4652a9/brjopthal00182-0080-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fccc/1039443/8a4d29276c7a/brjopthal00182-0079-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fccc/1039443/d53fe0ce2adf/brjopthal00182-0080-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fccc/1039443/aa398c4652a9/brjopthal00182-0080-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fccc/1039443/8a4d29276c7a/brjopthal00182-0079-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fccc/1039443/d53fe0ce2adf/brjopthal00182-0080-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fccc/1039443/aa398c4652a9/brjopthal00182-0080-b.jpg

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1
Iris neovascularisation in eyes with pseudoexfoliation syndrome.假性剥脱综合征患者眼部的虹膜新生血管形成
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Electron microscopy of the wall of iris vessels in eyes with and without exfoliation syndrome (pseudoexfoliation of the lens capsule).有和没有剥脱综合征(晶状体囊膜假性剥脱)的眼睛中虹膜血管壁的电子显微镜检查。
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Int Ophthalmol. 2023 Jun;43(6):1995-2002. doi: 10.1007/s10792-022-02599-6. Epub 2022 Nov 29.
2
Peripapillary atrophy in the unilateral exfoliation syndrome.单侧剥脱综合征中的视乳头周围萎缩
Graefes Arch Clin Exp Ophthalmol. 2004 Apr;242(4):301-5. doi: 10.1007/s00417-003-0843-1. Epub 2004 Jan 28.
3
Blood-aqueous barrier in pseudoexfoliation syndrome: evaluation by immunohistochemical staining of endogenous albumin.

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Ultrastructure of the wall of human iris vessels.
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Capillary hemorrhage in ascorbic-acid-deficient guinea pigs. Ultrastructural basis.
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The distribution of the exfoliation material in the iris from eyes with exfoliation syndrome (pseudoexfoliation of the lens capsule).剥脱综合征(晶状体囊膜假性剥脱)患者眼部虹膜中剥脱物质的分布情况。
Virchows Arch A Pathol Pathol Anat. 1970;351(2):168-78. doi: 10.1007/BF00542941.
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Electron microscopy of the wall of iris vessels in eyes with and without exfoliation syndrome (pseudoexfoliation of the lens capsule).有和没有剥脱综合征(晶状体囊膜假性剥脱)的眼睛中虹膜血管壁的电子显微镜检查。
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Tumor angiogenesis: iris neovascularization at a distance from experimental intraocular tumors.肿瘤血管生成:实验性眼内肿瘤远处的虹膜新生血管形成
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