丝裂霉素C和博来霉素治疗晚期宫颈癌：西南肿瘤学组的一项初步研究。
Mitomycin C and bleomycin in the treatment of far-advanced cervical cancer: a Southwest Oncology Group pilot study.
作者信息
Leichman L P, Baker L H, Stanhope C R, Samson M K, Fraile R J, Vaitkevicius V K, Hilgers R
出版信息
Cancer Treat Rep. 1980 Oct-Nov;64(10-11):1139-40.
PMID:6161699
Abstract
Under the auspices of the Southwest Oncology Group, Wayne State University tested a schedule using bleomycin and mitomycin C that was previously reported to give a response rate of 88%. In our patients the same regimen produced similar toxic effects but a far different response rate of 15.8% (one complete remission and two partial remissions). The only discernible difference in the two patient groups was the amount of radiation given prior to chemotherapy.
摘要
在西南肿瘤学组的支持下，韦恩州立大学对一种使用博来霉素和丝裂霉素C的方案进行了测试，该方案此前报道的缓解率为88%。在我们的患者中，相同的治疗方案产生了相似的毒性作用，但缓解率却大不相同，为15.8%（1例完全缓解和2例部分缓解）。两组患者唯一可察觉的差异是化疗前给予的放射剂量。
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