干扰素对人、小鼠和牛甲状腺组织中环磷酸腺苷 - 腺苷酸环化酶系统的影响。
Effects of interferon on the cAMP-adenylate cyclase system of human, mouse, and bovine thyroid tissue.
作者信息
Holmes S D, Chou M, Gutterman J, Field J B
出版信息
Metabolism. 1981 Feb;30(2):147-8. doi: 10.1016/0026-0495(81)90163-3.
PMID:6162073
Abstract
This report studied the action of interferon on the thyroidal adenylate cyclase-cAMP system. It was found that human interferon did not increase cAMP levels in human or bovine thyroid slices during a 60-min incubation. Mouse interferon also had no effect on cAMP levels in mouse thyroidal lobes over the 60-min incubation, nor did it increase adenylate cyclase activity in mouse homogenates.
摘要
本报告研究了干扰素对甲状腺腺苷酸环化酶 - cAMP系统的作用。结果发现，在60分钟的孵育过程中，人干扰素并未提高人或牛甲状腺切片中的cAMP水平。在60分钟的孵育过程中，小鼠干扰素对小鼠甲状腺叶中的cAMP水平也没有影响，并且它也没有增加小鼠匀浆中的腺苷酸环化酶活性。
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