Hagenbüchle O, Tosi M, Schibler U, Bovey R, Wellauer P K, Young R A
Nature. 1981 Feb 19;289(5799):643-6. doi: 10.1038/289643a0.
The sequence of 1,773-nucleotide major and 1,806-nucleotide minor mouse liver alpha-amylase mRNAs differ only with respect to approximately 30 additional residues at the extreme 5' terminus of the minor species. Comparison of the liver alpha-amylase mRNAs with their salivary gland counterpart reveals that these mRNAs share identical coding and 3'-noncoding sequences, but contain distinct 5'-terminal residues. These data suggest that all three mRNAs might be transcribed from the same gene.
1773个核苷酸的主要小鼠肝脏α-淀粉酶mRNA序列与1806个核苷酸的次要小鼠肝脏α-淀粉酶mRNA序列仅在次要序列5'末端的大约30个额外残基方面有所不同。将肝脏α-淀粉酶mRNA与其唾液腺对应物进行比较发现,这些mRNA共享相同的编码和3'非编码序列,但含有不同的5'末端残基。这些数据表明,所有这三种mRNA可能都转录自同一个基因。