Krizsa F, Borbényi Z, Arokszállásy E, Cserháti I
Folia Haematol Int Mag Klin Morphol Blutforsch. 1980;107(4):683-7.
The thrombopoietic serum activity was examined in rats during thrombocytopenia produced by bleeding or after treatment with antithrombocyte serum (ATS). 6 hours after both treatments the thrombopoietic activity of the serum, i.e. its content of thrombopoietin, is increased. After the ATS treatment of nephrectomized animals a similar increase of thrombopoietic activity as in normal animals could be achieved. In contrast to that, no similar increase of thrombopoietic activity was observed in nephrectomized animals after blood loss. According to the results of the authors the increase of thrombopoietic activity produced by different stimuli can be attributed to different mechanisms.
在通过放血诱导血小板减少的大鼠或用抗血小板血清（ATS）处理后的大鼠中，检测其血小板生成血清活性。两种处理后6小时，血清的血小板生成活性，即其血小板生成素含量，均升高。在对肾切除动物进行ATS处理后，可实现与正常动物类似的血小板生成活性增加。与此相反，肾切除动物失血后未观察到类似的血小板生成活性增加。根据作者的结果，不同刺激产生的血小板生成活性增加可归因于不同的机制。
