[High molecular weight albumins in normal and pathological pregnancies and under tocolytic therapy. Serum concentrations of beta-1-SP-1, IgM and alpha-2-macroglobulin].

Pregnancy protein beta-1-glycoprotein levels were determined in serum obtained from 100 women with undisturbed pregnancy and 35 women with high risk pregnancy. Concentrations lower than normal, i.e. below the 1s range, were found only in preeclampsia and in pregnancies with intrauterine growth retardation. Antepartum CTG scoring showed reasonable correlation with the SP-1 values. Due to its long half life time and its relation to the trophoblast, the diagnostic value of SP-1 in cases of placental insufficiency is limited.