[正常及病理妊娠和接受宫缩抑制剂治疗时的高分子量白蛋白。β-1-SP-1、IgM和α-2-巨球蛋白的血清浓度]
[High molecular weight albumins in normal and pathological pregnancies and under tocolytic therapy. Serum concentrations of beta-1-SP-1, IgM and alpha-2-macroglobulin].
作者信息
Siekmann U, Heilmann L
出版信息
Fortschr Med. 1980 Nov 6;98(41):1614-7.
PMID:6162765
Abstract
Pregnancy protein beta-1-glycoprotein levels were determined in serum obtained from 100 women with undisturbed pregnancy and 35 women with high risk pregnancy. Concentrations lower than normal, i.e. below the 1s range, were found only in preeclampsia and in pregnancies with intrauterine growth retardation. Antepartum CTG scoring showed reasonable correlation with the SP-1 values. Due to its long half life time and its relation to the trophoblast, the diagnostic value of SP-1 in cases of placental insufficiency is limited.
摘要
测定了100名正常妊娠女性和35名高危妊娠女性血清中的妊娠蛋白β-1-糖蛋白水平。仅在子痫前期和宫内生长受限的妊娠中发现浓度低于正常水平，即低于1s范围。产前CTG评分与SP-1值显示出合理的相关性。由于其半衰期长且与滋养层有关，SP-1在胎盘功能不全病例中的诊断价值有限。
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