Weber H, Heller S, Seulen P
Geburtshilfe Frauenheilkd. 1980 Apr;40(4):339-43. doi: 10.1055/s-2008-1039318.
Human placental lactogen (HPL) and beta 1-SP-1, a placental glycoprotein specific for pregnancy, were determined in 177 pregnant women with pre-eclampsia of varying severity. The serum levels of both hormones decrease during pregnancy in concordance to the severity of pre-eclampsia. In women with severe pre-eclampsia more than 50% showed extreme decreases of the serum concentrations of both hormones. Because of the simple methodology of the test, rapid availability of the results and a lower cost, the determination of the beta-1-SP-1 is perferable to the determination of HPL.
对177例不同严重程度子痫前期孕妇测定了人胎盘催乳素(HPL)和β1-SP-1(一种妊娠特异性胎盘糖蛋白)。在孕期,这两种激素的血清水平均随子痫前期严重程度的增加而下降。重度子痫前期患者中,超过50%的孕妇两种激素的血清浓度极度降低。由于检测方法简单、结果获取迅速且成本较低,因此测定β1-SP-1比测定HPL更可取。