利用巨噬细胞游走抑制试验评估金黄仓鼠可移植性黑色素瘤的抗原差异。
Use of the macrophage migration inhibition test to evaluate antigenic differences in golden hamster transplantable melanomas.
作者信息
Kozłowska K, Zurawska-Czupa B, Mierzewski P, Kostulak A
出版信息
Int J Cancer. 1980 Aug;26(2):211-5. doi: 10.1002/ijc.2910260213.
PMID:6162805
Abstract
Macrophage migration inhibition test in the presence of melanotic and amelanotic melanoma cells was analyzed by means of signal detection theory reasoning. The cellular immune response as measured by MMI test was stronger in hamsters grafted with amelanotic melanoma. A statistical analysis indicated that the amelanotic melanoma antigenic strength was greater than that of its melanotic counterpart.
摘要
通过信号检测理论推理分析了在有黑色素性和无黑色素性黑色素瘤细胞存在的情况下的巨噬细胞迁移抑制试验。通过巨噬细胞迁移抑制试验测定的细胞免疫反应在移植有无黑色素性黑色素瘤的仓鼠中更强。统计分析表明，无黑色素性黑色素瘤的抗原强度大于其黑色素性对应物。
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