Horn J, Heymer B, Burk R, Merkle N, Herfarth C
Langenbecks Arch Chir. 1980;353(1):9-17. doi: 10.1007/BF01261794.
Two different experimental procedures were used to induce pancreatitis in rats: distal ligature of the common bile duct and the Pfeffer method in modification of Nevalainen. It could be shown that consumption of complement can be demonstrated even in pancreatitis induced by other than immunological models. Further examination in decomplemented rats showed the possibility of inducing acute pancreatitis by the above-mentioned models, although of less intensity. Therefore, the complement system will be an important factor for the progress and intensity of the inflammation process.
胆总管远端结扎术以及改良的内瓦莱宁的普费弗方法。结果表明,即使在非免疫模型诱导的胰腺炎中也能证明补体的消耗。对补体缺失大鼠的进一步检查表明,上述模型有可能诱导急性胰腺炎,尽管炎症强度较低。因此,补体系统将是炎症过程进展和强度的一个重要因素。