脉络膜新生血管形成作为眼部弓形虫病的晚期并发症。

Choroidal neovascularization as a late complication of ocular toxoplasmosis.

作者信息

Fine S L, Owens S L, Haller J A, Knox D L, Patz A

出版信息

Am J Ophthalmol. 1981 Mar;91(3):318-22. doi: 10.1016/0002-9394(81)90283-x.

Abstract

Macular detachment caused by choroidal neovascularization in eyes with previous toxoplasmic infections is one possible explanation of sudden loss of visual acuity. Three patients with quiescent chorioretinal scars, presumed to be toxoplasmic in origin, developed choroidal neovascular membranes that caused sudden loss of visual acuity. In none of the three cases was there any ophthalmoscopic evidence of intraocular inflammation. In two patients, the choroidal neovascularization was subfoveal and, therefore, not suitable for photocoagulation. However, visual acuity in each of the affected eyes was only partially impaired (6/15 [20/50] in one patient and 6/30 [20/100] in the other). In the third patient, the choroidal neovascular membrane was treated with argon-laser photocoagulation. Two months after treatment, visual acuity in that eye was 6/9 (20/30), and there was angiographic evidence that the neovascular membrane had closed.

摘要

既往有弓形虫感染的眼睛中，脉络膜新生血管导致的黄斑脱离是视力突然丧失的一种可能解释。三名有静止性脉络膜视网膜瘢痕（推测起源于弓形虫感染）的患者发生了脉络膜新生血管膜，导致视力突然丧失。这三例患者均无任何眼底镜检查显示眼内炎症的证据。在两名患者中，脉络膜新生血管位于黄斑下，因此不适合进行光凝治疗。然而，每只患眼的视力仅部分受损（一名患者为6/15 [20/50]，另一名患者为6/30 [20/100]）。在第三名患者中，脉络膜新生血管膜接受了氩激光光凝治疗。治疗两个月后，该眼视力为6/9（20/30），血管造影显示新生血管膜已闭合。