Skorska I, Soubrane G, Coscas G
J Fr Ophtalmol. 1984;7(3):211-8.
Thirty six cases of toxoplasma chorioretinitis with fundus scars were studied. Subretinal neovascularization occurred in 7 cases out of 36. Angiographically, the new vessels were located either directly on the border of scar (5 cases) or at distance with feeder vessels arising from the scar. The identification of subretinal new vessels is easy during the early phase of angiography. At the late phase, the leakage from the membrane is usually difficult to distinguish from the staining of the scar. Leakage from these new vessels can cause a sudden decrease of visual acuity (from 0.4 to central scotoma) that is not associated with inflammatory signs. The natural history of these juxtafoveolar new vessels allows a useful final acuity (0.18 after a follow-up period from 5 to 42 months). The visual outcome of toxoplasmosis choroiditis without subretinal new vessels is usually around 0.5. In 3 eyes photocoagulation of new vessels was performed with improvement in the mean final acuity (0.3). In our cases the occurrence of subretinal new vessels happened only when the healing process was achieved, from 1 to 26 years after the acute chorioretinitis.
对36例伴有眼底瘢痕的弓形虫性脉络膜视网膜炎患者进行了研究。36例中有7例发生了视网膜下新生血管。血管造影显示,新生血管要么直接位于瘢痕边缘(5例),要么与源自瘢痕的供血血管有一定距离。在血管造影早期很容易识别视网膜下新生血管。在晚期,通常很难将膜的渗漏与瘢痕的染色区分开来。这些新生血管的渗漏可导致视力突然下降(从0.4降至中心暗点),且不伴有炎症体征。这些黄斑旁新生血管的自然病程可使最终视力达到有用水平(随访5至42个月后为0.18)。无视网膜下新生血管的弓形虫性脉络膜炎的视觉预后通常约为0.5。对3只眼的新生血管进行了光凝治疗,平均最终视力有所改善(0.3)。在我们的病例中,视网膜下新生血管仅在愈合过程完成时出现,即在急性脉络膜视网膜炎后1至26年。