Einhorn S, Blomgren H
J Clin Lab Immunol. 1981 Jan;5(1):31-6.
The effect of human interferon (IF) on lectin-dependent cellular cytotoxicity (LDCC) was studied in vitro. Using chicken erythrocytes as target cells in a 40h assay IF was found to inhibit this reaction at concentrations of 1,000 IF units/ml. When tumor cells were used as targets in a 4 h assay IF caused an increase in the cytotoxic activity of lymphocytes in the presence of PHA. However, when the spontaneous cytotoxic activity was subtracted from this value no major effect of IF on LDCC could be observed.
在体外研究了人干扰素（IF）对凝集素依赖性细胞毒性（LDCC）的影响。在40小时的试验中，以鸡红细胞作为靶细胞，发现IF在浓度为1000国际单位/毫升时可抑制该反应。在4小时的试验中，当使用肿瘤细胞作为靶细胞时，IF在PHA存在的情况下会导致淋巴细胞的细胞毒性活性增加。然而，从该值中减去自发细胞毒性活性后，未观察到IF对LDCC有主要影响。
