Vettermann W, Werner H J, Schmeisser S, Koch M A
Med Microbiol Immunol. 1981;169(2):75-81. doi: 10.1007/BF02171774.
Staining of lymphocytes from scrapie-infected STU mice with FITC-labelled anti-mouse Ig revealed disturbances in the capping process when compared with lymphocytes from mock-infected animals. Quantitative evaluation indicates that 10-15% of cells from scrapie-infected animals show an altered capping behaviour. These phenomena are discussed with special reference to the role of the lymphoreticular system in early scrapie agent replication.
用异硫氰酸荧光素标记的抗小鼠免疫球蛋白对感染羊瘙痒病的STU小鼠的淋巴细胞进行染色,结果显示,与模拟感染动物的淋巴细胞相比,其帽化过程受到干扰。定量评估表明,感染羊瘙痒病动物的细胞中有10%-15%表现出帽化行为改变。结合淋巴网状系统在羊瘙痒病病原体早期复制中的作用,对这些现象进行了讨论。