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放线菌素抑制大鼠中前列环素对胃黏膜的保护作用。

Actinomycin inhibits gastric mucosal protection by prostacyclin in rats.

作者信息

Balint G A, Varro V

出版信息

Prostaglandins. 1981 Feb;21(2):255-7. doi: 10.1016/0090-6980(81)90142-8.

DOI:10.1016/0090-6980(81)90142-8
PMID:6164077
Abstract

The protective effect of prostacyclin on gastric mucosal damage by indomethacin or restraint in rats was inhibited by actinomycin-C. Protection by prostacyclin may therefore require new protein synthesis.

摘要

前列环素对大鼠因吲哚美辛或束缚所致胃黏膜损伤的保护作用被放线菌素-C抑制。因此，前列环素的保护作用可能需要新的蛋白质合成。

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引用本文的文献

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Changes of endogenous prostacyclin-level in different experimental gastroduodenal ulcer models of rat.大鼠不同实验性胃十二指肠溃疡模型中内源性前列环素水平的变化。
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Prostacyclin acts in rat gastric (fundic) mucosa via the intracellular 'second messenger system'.
前列环素通过细胞内“第二信使系统”作用于大鼠胃（胃底）黏膜。
Agents Actions. 1985 Oct;17(1):46-7. doi: 10.1007/BF01966680.
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Gastric antral and fundic mucosal protein, DNA and RNA changes in different experimental ulcer models.不同实验性溃疡模型中胃窦和胃底黏膜蛋白质、DNA及RNA的变化
Agents Actions. 1985 Oct;17(1):89-91. doi: 10.1007/BF01966689.
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The effect of long-term prostacyclin treatment on the protein, DNA and RNA content of rat gastric fundic mucosa.长期前列环素治疗对大鼠胃底黏膜蛋白质、DNA和RNA含量的影响。
Agents Actions. 1985 Jul;16(5):404-6. doi: 10.1007/BF01982880.
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