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[长时间低血容量性低血压及复苏后期大脑皮质和内脏器官(肝脏和心脏)中总RNA和DNA浓度的变化]

[Changes in the concentrations of total RNA and DNA in the cerebral cortex and internal organs (liver and heart) after prolonged hypovolemic hypotension and in the post-resuscitation period].

作者信息

Kozhura V L

出版信息

Biull Eksp Biol Med. 1981 Feb;91(2):144-6.

PMID:6164413
Abstract

It was shown in experiments on dogs that after 4-hour hypovolemic hypotension the content of total RNA in brain cortex and myocardium homogenates decreased. In the liver, there was a significant decrease both in RNA and DNA content. In the postresuscitation period, the content of nucleic acids in the myocardium returned to normal after 14--21 days, and that in the liver after 3--4 months. The gray matter of the brain manifested a delayed lowering of DNA content (after 14--21 days), and the level of nucleic acid did not return ot normal over 3--4 months after resuscitation.

摘要

在对狗的实验中发现,4小时的低血容量性低血压后,大脑皮层和心肌匀浆中总RNA的含量降低。肝脏中RNA和DNA的含量均显著下降。在复苏期,心肌中的核酸含量在14 - 21天后恢复正常,肝脏中的核酸含量在3 - 4个月后恢复正常。大脑灰质的DNA含量出现延迟下降(14 - 21天后),复苏后3 - 4个月内核酸水平未恢复正常。

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