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[刺激胶原生成的形态学与生物化学研究]

[Morphologic and biochemical study of stimulated collagenogenesis].

作者信息

Dudnikova G N, Zaĭdenberg M A

出版信息

Biull Eksp Biol Med. 1981 Feb;91(2):236-8.

PMID:6164417
Abstract

A study was made of the effect of potassium orotate on wound healing. The duration of wound healing was 3 days less in animals given potassium orotate as compared to controls, with the rate of prolin-containing protein synthesis by fibroblasts and the rate of their egress into the intercellular space being increased. No excess fibrillogenesis was noted. Hydroxyprolin content in the granulation tissue of wounds differed little in control and in experimental animals.

摘要

对乳清酸钾对伤口愈合的影响进行了一项研究。与对照组相比,给予乳清酸钾的动物伤口愈合时间缩短了3天,成纤维细胞含脯氨酸蛋白的合成速率及其进入细胞间隙的速率均有所增加。未观察到过度的纤维形成。对照组和实验动物伤口肉芽组织中的羟脯氨酸含量差异不大。

相似文献

1
[Morphologic and biochemical study of stimulated collagenogenesis].[刺激胶原生成的形态学与生物化学研究]
Biull Eksp Biol Med. 1981 Feb;91(2):236-8.
2
[Effect of imidazole on collagenogenesis in granulation tissue of experimental wounds].[咪唑对实验性伤口肉芽组织中胶原生成的影响]
Biull Eksp Biol Med. 1981 Mar;91(3):357-9.
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[Stimulation of fibrillogenesis in granulation tissue].[肉芽组织中纤维形成的刺激作用]
Biull Eksp Biol Med. 1975 Dec;80(12):96-9.
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[Electron-radioautographic study of the effect of potassium orotate on RNA and protein synthesis in fibroblasts during experimental wound healing].[乳清酸钾对实验性伤口愈合过程中成纤维细胞RNA和蛋白质合成影响的电子放射自显影研究]
Biull Eksp Biol Med. 1983 Aug;96(8):115-8.
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[Autoradiographic study of stimulation of RNA synthesis in fibroblasts].[成纤维细胞中RNA合成刺激的放射自显影研究]
Biull Eksp Biol Med. 1978 Oct;86(10):488-91.
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[An autoradiographic and electron microscopic study of fibroblasts under conditions of stimulation of the wound process].[创伤过程刺激条件下成纤维细胞的放射自显影及电子显微镜研究]
Arkh Patol. 1976 Apr;38(4):13-8.
7
[Autoradiographic study of the rate of collagen synthesis under conditions of stimulation of the wound process].[创伤过程刺激条件下胶原蛋白合成速率的放射自显影研究]
Biull Eksp Biol Med. 1976 Oct;82(10):1256-8.
8
[Autoradiographic analysis of the effect of potassium orotate on the intensity of uridine-5 3H and proline-3H incorporation into wound fibroblasts].[乳清酸钾对尿苷-5 3H和脯氨酸-3H掺入伤口成纤维细胞强度影响的放射自显影分析]
Biull Eksp Biol Med. 1979 Jun;87(6):615-7.
9
[DNA synthesis by granulation tissue fibroblasts under conditions of stimulation of the wound process].[伤口愈合过程刺激条件下肉芽组织成纤维细胞的DNA合成]
Biull Eksp Biol Med. 1977 Sep;84(9):352-4.
10
The effect of tumor necrosis factor-alpha on wound healing. An experimental study.肿瘤坏死因子-α对伤口愈合的影响。一项实验研究。
Ann Chir Gynaecol Suppl. 1996;211:1-53.