慢性髓系白血病骨髓纤维化期的非原始细胞性脑膜白血病
Non-blastic meningeal leukemia during the myelofibrotic phase of chronic myeloid leukemia.
作者信息
Aversa P, Rambotti P, Falini B, Grignani F, Martelli M F
出版信息
Folia Haematol Int Mag Klin Morphol Blutforsch. 1981;108(1):72-5.
PMID:6164616
Abstract
Myeloblastic involvement of the central nervous system has been noted in the course of chronic myeloid leukemia in the blastic phase; meningeal leukemia in the chronic phase of CML is almost unknown. We report on a case of CML in which meningeal infiltration by cells of the granulocytes series in all stage of cellular maturation developed 15 years after initial diagnosis and seven months after a myelofibrotic transformation of the systemic disease.
摘要
在慢性髓性白血病的急变期病程中已注意到中枢神经系统的原始粒细胞受累情况；而慢性粒细胞白血病慢性期的脑膜白血病几乎无人知晓。我们报告了1例慢性粒细胞白血病患者，在初始诊断15年后且全身性疾病发生骨髓纤维化转化7个月后，出现了各个细胞成熟阶段的粒细胞系细胞的脑膜浸润。
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