多普勒LP试验在正常压力脑积水患者分流治疗中的预选择价值。

The preselection value of the Doppler LP test for shunt-therapy in patients with normal pressure hydrocephalus.

作者信息

Schoonderwaldt H C, Cho Chia Yuen G, Colon E J, Hommes O R, Notermans S L, Walder H A

出版信息

J Neurol. 1981;225(1):15-24. doi: 10.1007/BF00313457.

Abstract

The results of this study confirm the hypothesis that the simple innocuous Doppler LP test may be useful in obtaining information about CSFP-CBF (cerebrospinal fluid pressure-cerebral blood flow) relationships. The value of this test in predicting the clinical outcome of CSF shunting in patients with normal pressure hydrocephalus (NPH) was studied. Fourteen patients with NPH were examined; eight patients showed a positive and six patients a negative Doppler LP test. Seven of the eight patients with a positive test improved following the shunting procedure, but none of the six patients improved after operation. This study suggests that the Doppler LP test is a useful preoperative selection test in patients with NPH. In addition this study supports the hypothesis that CBF autoregulation may be impaired with NPH.

摘要

本研究结果证实了以下假设

简单无害的多普勒腰穿试验可能有助于获取有关脑脊液压力-脑血流量（CSFP-CBF）关系的信息。研究了该试验在预测正常压力脑积水（NPH）患者脑脊液分流临床结果方面的价值。对14例NPH患者进行了检查；8例患者多普勒腰穿试验呈阳性，6例患者呈阴性。8例试验阳性的患者中有7例在分流手术后病情改善，但6例试验阴性的患者术后均未改善。本研究表明，多普勒腰穿试验对NPH患者是一种有用的术前筛选试验。此外，本研究支持NPH可能损害脑血流量自动调节的假设。