Hartmann A, Alberti E
Arch Psychiatr Nervenkr (1970). 1978 Aug 22;225(4):291-306. doi: 10.1007/BF00343301.
Regional cerebral blood flow (rCBF) and regional cerebral blood volume (rCBV) were estimated in patients with communicating hydrocephalus, arteriosclerotic and presenile dementia. In all groups ischemic patterns were detected which did not allow any differential diagnostic separation between the patients. In some patients with communicating hydrocephalus reduction of cerebrospinal fluid pressure by lumbar puncture or ventriculoperipheral shunt respectively resulted in increase of rCBF and rCBV. This was not achieved in the other patients with dementia. Predominantly areas with ischemic flow values gained profit from reduction of CSF pressure. This was interpreted as a sign of regional damage to the autoregulation.
对交通性脑积水、动脉硬化性痴呆和早老性痴呆患者进行了局部脑血流量(rCBF)和局部脑血容量(rCBV)的评估。在所有组中均检测到缺血模式,这使得无法对患者进行鉴别诊断。在一些交通性脑积水患者中,分别通过腰椎穿刺或脑室 - 外周分流降低脑脊液压力后,rCBF和rCBV增加。而其他痴呆患者未出现这种情况。主要是缺血血流值区域从脑脊液压力降低中获益。这被解释为局部自动调节受损的迹象。