Terpstra O T, Dahl E P, Shellito P C, Malt R A
Arch Surg. 1981 Jun;116(6):800-2. doi: 10.1001/archsurg.1981.01380180056011.
Pancreaticobiliary secretions modulate compensatory hyperplasia after proximal small-bowel resection. To investigate the individual contributions of bile and pancreatic juice, levels of nucleic acids in ileal mucosa of the rat were examined 48 hours after performance of jejunectomy with selective exclusion of bile or pancreatic juice. Exclusion of bile alone inhibited the postresectional increase in levels of RNA and DNA. Exclusion of pancreatic juice (but provision of bile) did not inhibit a rise in ileal RNA or DNA levels after jejunectomy. Presence of bile seems to be one of the major elements in the early stages of adaptive hyperplasia of the ileum.
胰胆分泌物可调节近端小肠切除术后的代偿性增生。为了研究胆汁和胰液各自的作用，在选择性排除胆汁或胰液的情况下进行空肠切除术后48小时，检测大鼠回肠黏膜中的核酸水平。单独排除胆汁可抑制切除术后RNA和DNA水平的升高。排除胰液（但保留胆汁）并不抑制空肠切除术后回肠RNA或DNA水平的升高。胆汁的存在似乎是回肠适应性增生早期的主要因素之一。
