Bunt S M, Lund R D
Brain Res. 1981 May 4;211(2):399-404. doi: 10.1016/0006-8993(81)90712-5.
Intraocular HRP injections in E16-21 embryos show that during the normal development of the central optic projections in hooded and albino rats many optic axons grow through the chiasm into the contralateral eye. This retino-retinal projection disappears shortly after birth. This suggests that an initial, imprecise guidance of growing axons is followed by a selective elimination of axons taking aberrant pathways and failing to make appropriate synapses.
