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胰腺胰岛-腺泡细胞相互作用:淀粉酶信使核糖核酸水平由胰岛素决定。

Pancreatic islet-acinar cell interaction: amylase messenger RNA levels ar determined by insulin.

作者信息

Korc M, Owerbach D, Quinto C, Rutter W J

出版信息

Science. 1981 Jul 17;213(4505):351-3. doi: 10.1126/science.6166044.

DOI:10.1126/science.6166044
PMID:6166044
Abstract

Pancreatic amylase messenger RNA progressively decreases in rats rendered diabetic with streptozotocin. Insulin reverses this effect, inducing a selective decrease in amylase messenger RNA in the pancreas. Parotid amylase messenger RNA is not significantly affected by either diabetes or insulin.

摘要

用链脲佐菌素使大鼠患糖尿病后,胰腺淀粉酶信使核糖核酸逐渐减少。胰岛素可逆转这种效应,导致胰腺中淀粉酶信使核糖核酸选择性减少。糖尿病或胰岛素对腮腺淀粉酶信使核糖核酸均无显著影响。

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