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牛奶、酸奶和钙对兔胆固醇诱导的动脉粥样硬化的影响。

Influence of milk, yoghurt and calcium on cholesterol-induced atherosclerosis in rabbits.

作者信息

Thakur C P, Jha A N

出版信息

Atherosclerosis. 1981 May;39(2):211-5. doi: 10.1016/0021-9150(81)90071-x.

DOI:10.1016/0021-9150(81)90071-x
PMID:6166301
Abstract

Five groups of rabbits were studied to determine the effect of milk, yoghurt and calcium on cholesterol-induced hypercholesterolaemia and atherosclerosis. The experiment lasted for only 16 weeks. Yoghurt, calcium and milk reduced serum cholesterol levels in rabbits fed on the cholesterol diet. There was no significant difference in the cholesterol levels in the yoghurt and calcium groups. Yoghurt caused a greater extent of hypocholesterolaemia than milk (P less than 0.001). Aortic sudanophilia was maximal in the cholesterol-fed group, while there was no sudanophilia in the yoghurt-fed group. The milk and calcium groups showed an intermediate degree of sudanophilia. Aortic sudanophilia correlated with the serum cholesterol level (r = +0.65). It is suggested that calcium is an active factor in yoghurt, but that other hypocholesterolaemic agents may also be present.

摘要

研究了五组兔子,以确定牛奶、酸奶和钙对胆固醇诱导的高胆固醇血症和动脉粥样硬化的影响。实验仅持续了16周。酸奶、钙和牛奶降低了喂食胆固醇饮食的兔子的血清胆固醇水平。酸奶组和钙组的胆固醇水平没有显著差异。酸奶引起的降胆固醇程度比牛奶更大(P小于0.001)。喂食胆固醇组的主动脉苏丹红染色最深,而喂食酸奶组则没有苏丹红染色。牛奶组和钙组显示出中等程度的苏丹红染色。主动脉苏丹红染色与血清胆固醇水平相关(r = +0.65)。表明钙是酸奶中的一个活性因子,但也可能存在其他降胆固醇因子。

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Influence of milk, yoghurt and calcium on cholesterol-induced atherosclerosis in rabbits.牛奶、酸奶和钙对兔胆固醇诱导的动脉粥样硬化的影响。
Atherosclerosis. 1981 May;39(2):211-5. doi: 10.1016/0021-9150(81)90071-x.
2
Effect of skim milk and yogurt on serum lipids and development of sudanophilic lesions in cholesterol-fed rabbits.脱脂牛奶和酸奶对喂食胆固醇的兔子血清脂质及嗜苏丹病变发展的影响。
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DIETARY EFFECT OF MAGNESIUM ON CHOLESTEROL-INDUCED ATHEROSCLEROSIS OF RABBITS.镁对兔胆固醇诱导动脉粥样硬化的饮食影响
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Plant sterol ester-enriched milk and yoghurt effectively reduce serum cholesterol in modestly hypercholesterolemic subjects.富含植物甾醇酯的牛奶和酸奶能有效降低轻度高胆固醇血症患者的血清胆固醇水平。
Eur J Nutr. 2005 Jun;44(4):214-22. doi: 10.1007/s00394-004-0513-z. Epub 2004 Aug 17.

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