Ohba K, Shomura T, Tsuruoka T, Omoto S, Kojima M, Hisamatsu T, Inouye S, Niida T
J Antibiot (Tokyo). 1980 Nov;33(11):1236-42. doi: 10.7164/antibiotics.33.1236.
A new antibiotic, substance SF-1771, has been isolated for the fermentation broth of Streptomyces toyocaensis SF-1771. The antibiotic is highly active against Gram-positive and -negative bacteria and effective against sarcoma 180 cells of ascites type in mice. It belonged to the phleomycin-bleomycin group antibiotics, but has been differentiated from the known antibiotics by the physiochemical properties, chromatographic behaviors and amino acid analysis.
一种新的抗生素,即SF - 1771物质,已从丰加链霉菌SF - 1771的发酵液中分离出来。该抗生素对革兰氏阳性菌和阴性菌均具有高活性,并且对小鼠腹水型肉瘤180细胞有效。它属于博来霉素-平阳霉素类抗生素,但在理化性质、色谱行为和氨基酸分析方面与已知抗生素有所不同。