FR - 900137，一种新型抗生素。I. 产生该抗生素的微生物的分类学与发酵，以及抗生素的分离与特性分析

FR-900137, a new antibiotic. I. Taxonomy and fermentation of the organism, and isolation and characterization of the antibiotic.

作者信息

Kuroda Y, Goto T, Okamoto M, Yamashita M, Iguchi E, Kohsaka M, Aoki H, Imanaka H

出版信息

J Antibiot (Tokyo). 1980 Mar;33(3):272-9. doi: 10.7164/antibiotics.33.272.

DOI:10.7164/antibiotics.33.272

Abstract

A strain of Streptomyces, isolated from a soild sample and identified as Streptomyces unzenensis sp. nov. has been found to produce FR-900137, an interesting new antibiotic, containing phosphorus in its molecule. The antibiotic, obtained as white powder, was shown to inhibit a wide variety of Gram-positive and Gram-negative bacteria except Pseudomonas aeruginosa.

摘要

从一份土壤样品中分离出的一株链霉菌，经鉴定为新种云仙链霉菌，已发现它能产生FR - 900137，这是一种有趣的新型抗生素，其分子中含有磷。该抗生素呈白色粉末状，除铜绿假单胞菌外，对多种革兰氏阳性菌和革兰氏阴性菌均有抑制作用。