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血清中抗γ球蛋白因子的免疫组织化学检测(作者译)

[Immunohistochemical detection of antigammaglobulin factors in the serum (author's transl)].

作者信息

Geiler G, Schulze A

出版信息

Acta Histochem Suppl. 1980;22:309-11.

PMID:6166963
Abstract

Agglutination procedures for the detection of rheuma factors are inadequate concerning IgG and IgA factors and sensitivity to IgM factors, too, is generally limited. Both these disadvantages are to a great extent overcome when rheuma factors are fluorescence-marked with anti-human-gammaglobulin respectively with monospecific antiserums and when reaction steps according to Svartz and Schlossmann are applied to a microscope slide test. This test and the results of investigations of 101 cases (different joint diseases and healthy blood--donors) are described in this paper.

摘要

用于检测类风湿因子的凝集程序在检测IgG和IgA因子方面存在不足,而且对IgM因子的敏感性通常也有限。当分别用抗人γ球蛋白和单特异性抗血清对类风湿因子进行荧光标记,并将根据斯瓦尔茨和施洛斯曼方法的反应步骤应用于显微镜玻片试验时,这两个缺点在很大程度上得到了克服。本文描述了该试验以及对101例病例(不同关节疾病患者和健康献血者)的调查结果。

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