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肥胖症[超过55%]患者的胃酸与腮腺分泌(作者译)

[Gastric acid and parotid secretion in obesity [greater than 55%] (author's transl)].

作者信息

Malfertheiner P, Wechsler J G, Ditschuneit H H, Ditschuneit H

出版信息

Z Gastroenterol. 1981 Jun;19(6):261-6.

PMID:6167080
Abstract

In order to investigate exocrine secretory activity in obesity we studied gastric acid and parotid secretion in 22 massively obese patients (greater than 55% overweight); 15 normal persons were taken as controls. Basal and stimulated secretory values were determined. Basal acid output (BAO) in the obese (4,10 +/- 3,8 mval/h) was higher compared to normal (1,98 +/- 1,59 mval/h); the amylase activity in parotid saliva was reduced in the obese means = 195 U/ml (93,8-406) compared to normal means = 307 U/ml (145-652). These differences were not statistically significant. Maximal acid output (MAO) in the obese was within the normal range 17,6 +/- 8,98 mval/h (norm 16-25) despite it was expected, in a weight related manner, to be in a strongly hypersecretory range.

摘要

为了研究肥胖状态下的外分泌活动,我们对22例极度肥胖患者(超重超过55%)的胃酸和腮腺分泌情况进行了研究;选取15名正常人作为对照。测定了基础和刺激后的分泌值。肥胖患者的基础酸排出量(BAO)(4.10±3.8毫当量/小时)高于正常人(1.98±1.59毫当量/小时);肥胖患者腮腺唾液中的淀粉酶活性降低,平均值为195 U/ml(93.8 - 406),而正常人为307 U/ml(145 - 652)。这些差异无统计学意义。肥胖患者的最大酸排出量(MAO)在正常范围内,为17.6±8.98毫当量/小时(正常范围16 - 25),尽管按体重相关预期,其应处于强烈高分泌范围。

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