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惠普尔病的中枢神经系统受累情况。

Central nervous system involvement in Whipple's disease.

作者信息

Ludwig B, Bohl J, Haferkamp G

出版信息

Neuroradiology. 1981;21(5):289-93. doi: 10.1007/BF02100163.

DOI:10.1007/BF02100163
PMID:6167894
Abstract

A case of Whipple's disease is presented manifesting itself predominantly with neurological and mental symptoms but without gastrointestinal complaints. Although the first cranial CT in the fourth year of the disease was normal, the second, 1.5 years later, revealed intensive hypodensity of the white matter and cortical enhancement. CT findings are compared with autopsy results and a review of the pertinent literature is given.

摘要

本文报告一例惠普尔病,主要表现为神经和精神症状,无胃肠道不适。尽管病程第四年时首次头颅CT检查正常,但1.5年后的第二次检查显示白质密度明显减低及皮质强化。将CT表现与尸检结果进行了比较,并对相关文献进行了综述。

相似文献

1
Central nervous system involvement in Whipple's disease.惠普尔病的中枢神经系统受累情况。
Neuroradiology. 1981;21(5):289-93. doi: 10.1007/BF02100163.
2
Whipple's disease confined to the nervous system.局限于神经系统的惠普尔病。
J Neurol Neurosurg Psychiatry. 1981 Dec;44(12):1104-9. doi: 10.1136/jnnp.44.12.1104.
3
Cranial computed tomography in Whipple's disease.惠普尔病的头颅计算机断层扫描
J Comput Assist Tomogr. 1981 Apr;5(2):246-8.
4
[Cerebral involvement in Whipple's disease].
Rofo. 1990 Mar;152(3):336-9. doi: 10.1055/s-2008-1046879.
5
Whipple's disease confined to the central nervous system.局限于中枢神经系统的惠普尔病。
Neuroradiology. 1996 May;38(4):325-7. doi: 10.1007/BF00596579.
6
[Diagnostic significance of computerized tomography in cerebral manifestations caused by Whipple's disease].
Zentralbl Neurochir. 1986;47(4):301-10.
7
[Diagnosis of Whipple's disease].
Dtsch Med Wochenschr. 1980 Feb 8;105(6):180-1. doi: 10.1055/s-2008-1070629.
8
Whipple's disease with cerebral involvement.伴有脑部受累的惠普尔病。
Postgrad Med J. 1990 Sep;66(779):724-6. doi: 10.1136/pgmj.66.779.724.
9
[Computertomographical findings in cerebral Whipple's disease (author's transl)].
Fortschr Neurol Psychiatr. 1981 Jun;49(6):232-5. doi: 10.1055/s-2007-1002329.
10
Whipple's disease confined to the brain: a case studied clinically and pathologically.局限于脑部的惠普尔病:一例临床与病理研究病例
J Neurol Neurosurg Psychiatry. 1977 Sep;40(9):901-9. doi: 10.1136/jnnp.40.9.901.

引用本文的文献

1
Isolated central nervous system Whipple disease.孤立性中枢神经系统惠普尔病。
Surg Neurol Int. 2022 Oct 21;13:477. doi: 10.25259/SNI_591_2022. eCollection 2022.
2
Neuro-Whipple confirmed five years after a presumptive diagnosis of a primitive CNS vasculitis.
J Neurol. 2008 Jun;255(6):925-6. doi: 10.1007/s00415-008-0597-0. Epub 2008 May 7.
3
Diffuse lesions in the CNS revealed by MR imaging in a case of Whipple disease.惠普尔病一例中磁共振成像显示的中枢神经系统弥漫性病变。

本文引用的文献

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Whipple's disease (lipophagia granulomatosis); report of 1 case.
Gastroenterology. 1950 Jun;15(2):366-9.
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Encephalopathy in Whipple's disease. A histochemical study.
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Light and electron microscopic studies of Whipple's disease.惠普尔病的光镜和电镜研究。
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Central nervous system involvement in Whipple's disease.
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Gadolinium-enhanced MRI in cerebral Whipple's disease.钆增强磁共振成像在脑型惠普尔病中的应用
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WHIPPLE'S DISEASE: LIGHT AND ELECTRON MICROSCOPE CORRELATION OF JEJUNAL MUCOSAL HISTOLOGY WITH ANTIBIOTIC TREATMENT AND CLINICAL STATUS.惠普尔病:空肠黏膜组织学的光镜与电镜观察结果与抗生素治疗及临床状态的相关性
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CEREBRAL COMPLICATIONS OF WHIPPLE'S DISEASE.
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7
AN ELECTRON MICROSCOPIC STUDY OF THE STRUCTURE OF THE SMALL INTESTINE IN WHIPPLE'S DISEASE.惠普尔病中小肠结构的电子显微镜研究
J Ultrastruct Res. 1964 Feb;10:124-44. doi: 10.1016/s0022-5320(64)90026-7.
8
Involvement of central nervous system in Whipple's disease.惠普尔病累及中枢神经系统。
Neurology. 1963 May;13:397-404. doi: 10.1212/wnl.13.5.397.
9
The effect of antibiotic and steroid therapy in Whipple's disease.抗生素和类固醇疗法在惠普尔病中的作用。
Gastroenterology. 1963 Feb;44:112-6.
10
Encephalopathy in a case of Whipple's disease.惠普尔病一例中的脑病
J Neurol Neurosurg Psychiatry. 1963 Jun;26(3):203-210. doi: 10.1136/jnnp.26.3.203.