Shvetsova T P, Zasukhina G D, Bektemirov T A, Andronova A V, Barkova E P
Genetika. 1981;17(7):1294-8.
Interferon having the activity 25-37 and 375 IU/ml decreases the frequency of chromosome aberrations induced with the cancerogen 4-nitroquinoline-1-oxide in diploid human cells. The protective effect of interferon is not connected with stimulation or inhibition of cell division. It has been revealed that interferon with the activity 25-37 IU/ml has a stimulating effect on mitotic activity of cells, while interferon with the activity 375 IU/ml inhibits cell division.
活性为25 - 37和375国际单位/毫升的干扰素可降低二倍体人类细胞中由致癌物4 - 硝基喹啉 - 1 - 氧化物诱导的染色体畸变频率。干扰素的保护作用与细胞分裂的刺激或抑制无关。已发现活性为25 - 37国际单位/毫升的干扰素对细胞的有丝分裂活性有刺激作用，而活性为375国际单位/毫升的干扰素则抑制细胞分裂。
