Schiffmann D, Koschel K
Med Microbiol Immunol. 1981;169(4):281-9. doi: 10.1007/BF02125527.
The antiviral activity of mouse fibroblast interferon against vesicular stomatitis virus was investigated in L-929 mouse fibroblasts and the ganglioside-deficient L-929 mutant cells (ATCC clone NCTC 2071). Although it has been widely reported that gangliosides serve as primary receptors for interferon at the cellular membrane, only a small difference in interferon sensitivity was observed between the wild-type L-929 and the ganglioside-deficient NCTC 2071 cells. It was not possible, however, to overcome this difference by administration of exogenous gangliosides.
在L-929小鼠成纤维细胞和神经节苷脂缺陷型L-929突变细胞（美国典型培养物保藏中心克隆NCTC 2071）中研究了小鼠成纤维细胞干扰素对水疱性口炎病毒的抗病毒活性。尽管已有广泛报道称神经节苷脂是干扰素在细胞膜上的主要受体，但野生型L-929细胞和神经节苷脂缺陷型NCTC 2071细胞之间在干扰素敏感性上仅观察到微小差异。然而，通过给予外源性神经节苷脂并不能克服这种差异。
