白细胞干扰素和成纤维细胞干扰素对转化的人细胞中细胞生长和病毒生长抑制作用的比较。

Comparison of the suppression of cell and virus growth in transformed human cells of leukocyte and fibroblast interferon.

作者信息

Kuwata T, Fuse A, Suzuki N, Morinaga N

出版信息

J Gen Virol. 1979 May;43(2):435-9. doi: 10.1099/0022-1317-43-2-435.

Abstract

The effects of human leukocyte interferon (Le-IF) and fibroblast interferon (F-IF) on the growth of the transformed human cell lines, RSa and RSb, were compared. Both were considerably more sensitive to F-IF than to Le-IF. Two cell lines, IFr and F-IFr, derived from the RSa cell line, were resistant to the anticellular effects of Le-IF, but less resistant to those of F-IF.

摘要

比较了人白细胞干扰素（Le-IF）和成纤维细胞干扰素（F-IF）对转化的人细胞系RSa和RSb生长的影响。两者对F-IF的敏感性均明显高于对Le-IF的敏感性。从RSa细胞系衍生而来的两个细胞系IFr和F-IFr对Le-IF的抗细胞作用具有抗性，但对F-IF的抗细胞作用抗性较弱。