Ferguson G G, Brett D C, Peerless S J, Barr H W, Girvin J P
Can J Neurol Sci. 1981 Aug;8(3):207-14. doi: 10.1017/s0317167100043225.
Seventy-five patients were treated between March 1976 and June 1980 for classical idiopathic tic douloureux. Fifty-five patients underwent percutaneous trigeminal rhizotomy (PTR) and twenty-four had posterior fossa microvascular decompression (MVD) of the trigeminal nerve. Four patients had both procedures. In the PTR group, 4% were immediate failures, 42% had a delayed recurrence of pain, while 54% remained totally pain free with an average follow-up of 30 months. In the MVD group, 12% were immediate failures, 17% had a delayed recurrence of pain, and 71% have remained free of pain with a average follow-up of 28 months. Neither procedure can be regarded as ideal surgical treatment for patients with pain refractory to medical treatment. Percutaneous rhizotomy has an established place because of its safety, particularly in elderly patients. A high rate of recurrent pain is to be expected. Microvascular decompression has appeal in younger patients because of its non-destructive nature but the long term efficacy of the procedure is not known.
1976年3月至1980年6月期间,75例典型特发性三叉神经痛患者接受了治疗。55例患者接受了经皮三叉神经根切断术(PTR),24例接受了三叉神经后颅窝微血管减压术(MVD)。4例患者接受了两种手术。在PTR组中,4%为即刻失败,42%出现疼痛延迟复发,而54%在平均30个月的随访中完全无痛。在MVD组中,12%为即刻失败,17%出现疼痛延迟复发,71%在平均28个月的随访中无疼痛。对于药物治疗无效的疼痛患者,这两种手术都不能被视为理想的手术治疗方法。经皮神经根切断术因其安全性,尤其是在老年患者中,具有既定的地位。预计会有较高的疼痛复发率。微血管减压术因其非破坏性的性质在年轻患者中具有吸引力,但该手术的长期疗效尚不清楚。