Williams A R, Chater B V, Allen K A, Sanderson J H
J Clin Ultrasound. 1981 Apr;9(4):145-51. doi: 10.1002/jcu.1870090402.
Three sequential blood samples were drawn from arms of adult human volunteers by means of a cannula technique, and the plasma levels of beta-thromboglobulin (beta-TG an index of platelet damage) were measured. Ultrasound (0.75 MHz, continuous wave; spatially averaged intensity 0.34 to 0.5 W/cm-2) was applied to the blood vessels while the second sample of each series was being taken. No elevation of beta-TG was detected, indicating that under these conditions ultrasonic irradiation had not damaged an appreciable number of platelets. There was, however, an indication of decreased platelet sensitivity following insonation; and it is postulated that this may be the result of either increased production or secretion of the potent endothelial platelet inhibitor, prostacyclin, or both.
通过套管技术从成年人类志愿者的手臂采集了三份连续的血样，并测量了血浆中β-血小板球蛋白（β-TG，血小板损伤指标）的水平。在采集每个系列的第二份样本时，对血管施加超声（0.75 MHz，连续波；空间平均强度0.34至0.5 W/cm²）。未检测到β-TG升高，这表明在这些条件下超声照射并未损伤相当数量的血小板。然而，有迹象表明超声作用后血小板敏感性降低；据推测，这可能是强效内皮血小板抑制剂前列环素产生或分泌增加，或两者兼有的结果。
