Cordova C, Musca A, Violi F, Alessandri C, Perrone A, Balsano F
Eur J Respir Dis. 1985 Jan;66(1):9-12.
Platelet aggregation (PA) and plasma beta-thromboglobulin (beta TG) values were evaluated in 40 patients affected by chronic airway obstruction (CAO). PA and beta TG were significantly higher than those observed in normal subjects. Beta TG plasma levels were inversely correlated with PaO2, directly with PaCO2 and [H+]. Two h after a venesection of 300-400 ml, no change of beta TG and PA was seen in 10 healthy subjects, while a significant increase of beta TG and PA values was observed in 29 patients. The investigation suggests that in patients with CAO in vivo platelet activation is present.
对40例慢性气道阻塞（CAO）患者的血小板聚集（PA）和血浆β-血小板球蛋白（βTG）值进行了评估。PA和βTG显著高于正常受试者。βTG血浆水平与动脉血氧分压（PaO2）呈负相关，与动脉血二氧化碳分压（PaCO2）和氢离子浓度（[H+]）呈正相关。对10名健康受试者进行300 - 400 ml静脉放血两小时后，βTG和PA无变化，而29例患者的βTG和PA值显著升高。该研究表明，CAO患者体内存在血小板活化。
