Wise W S, Kandaswamy K
Arch Pathol Lab Med. 1981 Nov;105(11):622-5.
A prospective study compared five different assays for serum prostatic acid phosphatase in the detection of carcinoma of the prostate gland. The assays included two radioimmunoassay procedures, one counterimmunoelectrophoresis procedure, and an enzymatic procedure using alpha-naphthol phosphate substrate with and without sodium tartrate inhibition. The patients' hospital records were reviewed, as were all available surgical histology slides. The patients were divided into four groups: prostatic carcinoma, benign prostatic hypertrophy, other carcinomas (besides prostatic carcinoma), and no related disease states (that would be expected to give elevated acid phosphatase levels). The results were analyzed with respect to sensitivity, specificity, predictive value of a positive result, predictive value of a negative result, and efficiency of the assays.
一项前瞻性研究比较了五种不同的血清前列腺酸性磷酸酶检测方法在前列腺癌检测中的效果。这些检测方法包括两种放射免疫测定法、一种对流免疫电泳法，以及一种使用α-萘酚磷酸底物且有或没有酒石酸钠抑制作用的酶法。对患者的医院记录以及所有可用的手术组织学切片进行了审查。患者被分为四组：前列腺癌、良性前列腺增生、其他癌症（除前列腺癌外）以及无相关疾病状态（预期不会导致酸性磷酸酶水平升高）。针对检测方法的敏感性、特异性、阳性结果预测值、阴性结果预测值和效率对结果进行了分析。
