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对感染劳斯氏白血病病毒的Balb/c小鼠血清中可溶性抗原的免疫化学检测。

Immunochemical examination of soluble antigens in the serum of Balb/c mice infected with Rauscher leukaemia virus.

作者信息

Tóth F D, Váczi L, Kása M, Karsai T

出版信息

Acta Microbiol Acad Sci Hung. 1976;23(2):185-90.

PMID:61713
Abstract

The serum of Balb/c mice infected with Rauscher leukaemia virus contained soluble antigens characterized by alpha2 and beta globulin electrophoretic mobility; their respective molecular weights, as determined with gel filtration, were 40 000 and 120 000. The antigens differed in specificity and their corresponding determinants were present on the surface of leukaemic cells. For Balb/c mice both antigens, for DBA/1 and C57B1/10Sn mice only the antigen showing alpha2 mobility was immunogenic.

摘要

感染劳斯氏白血病病毒的Balb/c小鼠血清中含有可溶性抗原,其特征为具有α2和β球蛋白电泳迁移率;通过凝胶过滤测定,它们各自的分子量分别为40000和120000。这些抗原在特异性上有所不同,其相应的决定簇存在于白血病细胞表面。对于Balb/c小鼠,两种抗原都具有免疫原性,而对于DBA/1和C57B1/10Sn小鼠,只有显示α2迁移率的抗原具有免疫原性。

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Immunochemical examination of soluble antigens in the serum of Balb/c mice infected with Rauscher leukaemia virus.对感染劳斯氏白血病病毒的Balb/c小鼠血清中可溶性抗原的免疫化学检测。
Acta Microbiol Acad Sci Hung. 1976;23(2):185-90.
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