Wenhe Z, Yucun S
Int J Neurosci. 1981;15(3):147-9. doi: 10.3109/00207458108985907.
The changes in levels of 5-hydroxytryptamine (5-HT), 5-hydroxyindoleacetic acid (5-HIAA), norepinephrine (NE), 3-methoxy-4-hydroxyphenylethyleneglycol sulphate (MHPG-SO4) and dopamine (DA) of rat brain were studied after electric acupuncture stimulation (EAS). We found that the mean values of cerebral 5-HT and 5-HIAA after EAS were increased 16% (p less than 0.001) and 24% (p less than 0.01) respectively, significantly higher than those of controls, whereas the mean value of cerebral NE was decreased 14% (p less than 0.01), significantly lower than that of the controls. The cerebral MHPG-SO4 and DA in both groups showed no significant difference. In a second series of experiments with another group of rats, EAS was administered once a day for ten days. There was no statistical significance between the treated group and the control group in the differences in brain contents of all three monoamine neurotransmitters and 5-HIAA.
在电针刺激（EAS）后，对大鼠脑内5-羟色胺（5-HT）、5-羟吲哚乙酸（5-HIAA）、去甲肾上腺素（NE）、3-甲氧基-4-羟基苯乙二醇硫酸盐（MHPG-SO4）和多巴胺（DA）水平的变化进行了研究。我们发现，电针刺激后脑内5-HT和5-HIAA的平均值分别升高了16%（p<0.001）和24%（p<0.01），显著高于对照组，而脑内NE的平均值降低了14%（p<0.01），显著低于对照组。两组脑内MHPG-SO4和DA无显著差异。在另一组大鼠的第二项实验系列中，每天进行一次电针刺激，持续十天。在所有三种单胺类神经递质和5-HIAA的脑内含量差异方面，治疗组和对照组之间无统计学意义。
