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[冠状动脉血流监测性受限情况下血液及心肌的激肽系统]

[Kinin system of the blood and myocardium in monitored limitation of the coronary blood flow].

作者信息

Gunina L M

出版信息

Vopr Med Khim. 1981 Sep-Oct;27(5):630-3.

PMID:6171933
Abstract

Components of the blood kinin system as well as concentration of kininogen and kininase activity were studied in various myocardial structures after controlled restriction of coronary circulation by 30%, 50%, 70% and 90% within 30 min. As blood supply of heart decreased, activation of kallikrein, decrease in content of kininogen and inhibition of kininase activity in blood were observed. These alterations were detected also in myocardium; they were especially distinct in the ischemic zone.

摘要

在30分钟内将冠状动脉循环控制限制30%、50%、70%和90%后,研究了血液激肽系统的组成成分以及激肽原浓度和激肽酶活性在各种心肌结构中的情况。随着心脏血液供应减少,观察到血液中激肽释放酶的激活、激肽原含量的降低以及激肽酶活性的抑制。这些改变在心肌中也被检测到;它们在缺血区尤为明显。

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