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泛发性斑秃患者的自发细胞介导细胞毒性(SCMC)

Spontaneous cell-mediated cytotoxicity (SCMC) in patients with alopecia universalis.

作者信息

Gu S Q, Ros A M, Thyresson N, Wasserman J

出版信息

Acta Derm Venereol. 1981;61(5):434-7.

PMID:6172934
Abstract

The spontaneous cell-mediated cytotoxicity (SCMC) of unfractionated lymphocytes was determined in 5 patients with alopecia universalis (AU). The target cells used were K562 and Chang cell lines. All patients had an increased SCMC as compared with age- and sex-matched donors. The results indicate that SCMC against K562 cells is more pronounced than that against Chang cells.

摘要

对5例泛发性斑秃(AU)患者未分离淋巴细胞的自发细胞介导细胞毒性(SCMC)进行了测定。所用靶细胞为K562和Chang细胞系。与年龄和性别匹配的供者相比,所有患者的SCMC均升高。结果表明,针对K562细胞的SCMC比针对Chang细胞的更明显。

相似文献

1
Spontaneous cell-mediated cytotoxicity (SCMC) in patients with alopecia universalis.泛发性斑秃患者的自发细胞介导细胞毒性(SCMC)
Acta Derm Venereol. 1981;61(5):434-7.
2
In vitro cell-mediated cytotoxicity in primary biliary cirrhosis and chronic hepatitis. Dysfunction of spontaneous cell-mediated cytotoxicity in primary biliary cirrhosis.原发性胆汁性肝硬化和慢性肝炎中的体外细胞介导细胞毒性。原发性胆汁性肝硬化中自发细胞介导细胞毒性的功能障碍。
J Clin Invest. 1977 Nov;60(5):1116-28. doi: 10.1172/JCI108863.
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Blood lymphocyte subpopulations and antibody dependent, cell-mediated cytotoxicity (ADCC) in alopecia areata and universalis.斑秃和全秃患者的血液淋巴细胞亚群及抗体依赖性细胞介导的细胞毒性(ADCC)
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Spontaneous cytotoxicity of cultured human cell lines mediated by normal peripheral blood lymphocytes. III. Kinetic parameters.
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Spontaneous cytotoxicity (SCMC) of normal human lymphocytes against a human melanoma cell line: a phenomenon due to a lymphotoxin-like mediator.正常人淋巴细胞对人黑色素瘤细胞系的自发细胞毒性(SCMC):一种由类淋巴毒素介质引起的现象。
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Comparison of the natural cell mediated and antibody dependent cell mediated cytotoxicity measured as a function of target cell number in patients with mammary tumors and healthy female blood donors.在患有乳腺肿瘤的患者和健康女性献血者中,作为靶细胞数量函数测量的天然细胞介导的细胞毒性和抗体依赖性细胞介导的细胞毒性的比较。
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Suppressor cell number and function in alopecia areata.斑秃中抑制性细胞的数量与功能
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引用本文的文献

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In situ demonstration of T cells in alopecia areata.斑秃中T细胞的原位显示
Arch Dermatol Res. 1982;273(1-2):155-8. doi: 10.1007/BF00509041.
2
Hair-raising notions and lotions.令人毛骨悚然的观念和洗剂。
Br Med J (Clin Res Ed). 1982 Feb 13;284(6314):445-6. doi: 10.1136/bmj.284.6314.445.