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泛发性斑秃患者的自发细胞介导细胞毒性(SCMC)

Spontaneous cell-mediated cytotoxicity (SCMC) in patients with alopecia universalis.

作者信息

Gu S Q, Ros A M, Thyresson N, Wasserman J

出版信息

Acta Derm Venereol. 1981;61(5):434-7.

PMID:6172934
Abstract

The spontaneous cell-mediated cytotoxicity (SCMC) of unfractionated lymphocytes was determined in 5 patients with alopecia universalis (AU). The target cells used were K562 and Chang cell lines. All patients had an increased SCMC as compared with age- and sex-matched donors. The results indicate that SCMC against K562 cells is more pronounced than that against Chang cells.

摘要

对5例泛发性斑秃(AU)患者未分离淋巴细胞的自发细胞介导细胞毒性(SCMC)进行了测定。所用靶细胞为K562和Chang细胞系。与年龄和性别匹配的供者相比,所有患者的SCMC均升高。结果表明,针对K562细胞的SCMC比针对Chang细胞的更明显。

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