Gromova E A, Katkov Iu A, Kalmykov V L, Bobkova N V
Zh Vyssh Nerv Deiat Im I P Pavlova. 1981 Nov-Dec;31(6):1238-46.
The ability for learning was studied in two groups of Wistar line rats divided by susceptibility to the audiogenic stress-stimulation as compared with the monoamines level in various brain structures. The best ability to learn avoidance reaction in a shuttlebox was shown by animals non-resistant to the stress stimulus as compared with the resistant rats, which correlated positively with the exploratory activity in "the open field". The distinct feature of the animals non-resistant to the stress stimulation consisted in a higher reactivity of the monoamine systems, mainly of the noradrenergic system. This group of animals was also characterized by a higher dopamine content and a lower noradrenaline content in the brain-stem. Decreased activity of the brain dopamine-beta-hydroxylase in animals non-resistant to the stress stimulus, has been suggested.
以对听源性应激刺激的易感性进行分组，研究了两组Wistar系大鼠的学习能力，并将其与不同脑结构中的单胺水平进行比较。与应激刺激耐受大鼠相比，对应激刺激无抗性的动物在穿梭箱中表现出最佳的回避反应学习能力，这与“旷场”中的探索活动呈正相关。对应激刺激无抗性的动物的显著特征在于单胺系统，主要是去甲肾上腺素能系统的反应性较高。这组动物的脑干中多巴胺含量较高，去甲肾上腺素含量较低。有人提出，对应激刺激无抗性的动物脑多巴胺-β-羟化酶活性降低。
