Norn M S
Acta Ophthalmol (Copenh). 1980 Dec;58(6):991-9. doi: 10.1111/j.1755-3768.1980.tb08327.x.
A quantitative cytologic analysis of the sediment of 5 ml of saline (0.9%) washed through the lacrimal drainage system of 25 normal and 84 diseased eyes revealed that the cytological picture reflects the conditions in the lacrimal passages and not in the conjunctiva. Neutrophilia was seen to become increasingly frequent with slowing down of the flow through the lacrimal passage, estimated on the basis of dye dilution in the lacrimal river and dye dilution in the fluid washed through the lacrimal drainage system, and also by the spontaneous passing of the dye to the nasopharynx. Neutrophilia was present in no more than 8% of normal eyes, as against 69% of eyes with epiphora, 83% with infectious conjunctivitis, 40% with conjunctivitis sicca, and 50% with chronic simple conjunctivitis. Neither lymphocytosis nor eosinophilia was seen in any normal eyes. Erythrocytes were admixed artificially by washing through and probing. Granules were absent in normal eyes, but present in 5% of the diseased eyes, while hairs were found in 4 and 14%, respectively, and the fungus Alternaria in 4 and 1%.
对25只正常眼睛和84只患病眼睛的泪道系统用5毫升生理盐水（0.9%）冲洗后的沉淀物进行定量细胞学分析，结果显示细胞学图像反映的是泪道而非结膜的状况。根据泪河中的染料稀释度、经泪道系统冲洗的液体中的染料稀释度以及染料自然流入鼻咽部的情况估计，随着泪道中液体流动减慢，嗜中性粒细胞增多的情况越来越常见。正常眼睛中嗜中性粒细胞增多的比例不超过8%，相比之下，溢泪症患者眼睛中该比例为69%，感染性结膜炎患者为83%，干眼症患者为40%，慢性单纯性结膜炎患者为50%。正常眼睛中均未出现淋巴细胞增多或嗜酸性粒细胞增多的情况。通过冲洗和探查人为混入了红细胞。正常眼睛中没有颗粒，但患病眼睛中有5%出现颗粒，分别有4%和14%的患病眼睛中发现毛发，4%和1%的患病眼睛中发现链格孢属真菌。
