Boey J, Wong J, Ong G B
Ann Surg. 1982 Apr;195(4):513-8. doi: 10.1097/00000658-198204000-00022.
Pelvic exenteration provided worthwhile palliation and achieved a cumulative five-year survival rate of 38.8% in 49 patients who had carcinoma of the lower colon or rectum infiltrating adjoining pelvic viscera. Survival and the disease-free period were not significantly different after total or posterior exenteration. The stage of disease was the major determinant of outcome: five-year survival rates averaged 51.8% and 28.8% for Stages II and III, respectively. Hospital mortality (26.9%) after total exenteration was chiefly due to technical mishaps, and the inclusion of many high-risk but symptomatic elderly patients. Complete clearance of locally advanced colorectal cancer by pelvic exenteration is indicated in fit patients, especially those with Stage II disease.
盆腔脏器清除术提供了有价值的姑息治疗，49例下结肠或直肠癌浸润相邻盆腔脏器的患者累积五年生存率为38.8%。全盆腔脏器清除术或后盆腔脏器清除术后的生存率和无病生存期无显著差异。疾病分期是结果的主要决定因素：II期和III期的五年生存率分别平均为51.8%和28.8%。全盆腔脏器清除术后的医院死亡率（26.9%）主要归因于技术失误以及纳入了许多高危但有症状的老年患者。对于身体状况适宜的患者，尤其是II期疾病患者，建议通过盆腔脏器清除术彻底清除局部晚期结直肠癌。
