Perino A, Daniele E, Alaimo R, Aragona F, Genova G, Campesi G
Eur J Gynaecol Oncol. 1981;2(2):64-9.
Endodermal sinus tumor (EST) of the ovary is a germ cell tumor that is now recognized more frequently than in the past. Since problems concerning natural history, prognosis and therapy of these neoplasms are not entirely resolved, it should be underlined the need to report new cases. The authors describe four cases of EST with reference to serial alphafetoprotein determination by radioimmunoassay; they also emphasize the importance of this technique as a very sensitive method in monitoring therapy and in detecting recurrences of disease even before any clinical evidence.
卵巢内胚窦瘤（EST）是一种生殖细胞肿瘤，如今其被发现的频率比过去更高。由于这些肿瘤的自然病史、预后及治疗方面的问题尚未完全解决，应当强调报告新病例的必要性。作者报告了4例内胚窦瘤病例，并提及通过放射免疫测定法对甲胎蛋白进行系列测定；他们还强调了该技术作为一种非常敏感的方法在监测治疗以及在疾病复发临床证据出现之前检测复发方面的重要性。
